Platelets (platelets or platelets) are blood components that contain ‘growth factors’ necessary to restore the damaged tissues in our body and return them to their natural state. The therapeutic power of thrombocytes began to be studied in the 1970s, and research on this subject gradually increased. The growth factors of platelets are effective in the proliferation and differentiation of epithelial, bone, and connective tissue cells. Due to these properties, it is increasingly used in cosmetic dermatology. The most common areas of use include hair loss seen in men and women, and anti-aging and rejuvenating applications on the face and neck décolleté.
Platelet-rich plasma (Platelet-Rich Plasma-PRP) is the process of placing approximately 13-15 cc of blood taken from the person into a special tube and returning the platelet-rich plasma obtained after centrifugation to the same person by injection. The purpose of this process is to deliver more thrombocytes and growth factors to the tissue that can be transported to the area through the bloodstream.
Hair loss is one of the common problems that many people can experience. Hair loss, which can have many different reasons, can be offered different treatment alternatives to the patients with a detailed examination and subsequent examinations. PRP can be used especially for early male pattern hair loss and diffuse hair loss called diffuse alopecia. Scalp PRP applications are usually performed with fine needles. In other words, the serum obtained is given under the skin at certain intervals, especially in the area where hair thinning is observed. PRP can be used alone in hair loss or can be used with hair mesotherapy. It can also be applied as a supportive treatment before and after hair transplantation.
PRP treatment is a method that can also be used in skin rejuvenation. Human skin ages in two ways. First, it is a gradual decline that is due to changes in metabolism over time, called internal aging and is often due to genetic factors. The second reason for aging is aging due to the cumulative effect of environmental harmful factors, known as external aging, the main ones being cigarette, sunlight, and chemical exposure. The process that starts in the form of fine wrinkles and spots is becoming more and more pronounced. It is often very difficult to reverse this process, especially in advanced cases.
First of all, preventing factors that we can prevent, such as not smoking, protecting from the sun, and then applying procedures to reverse the damage that has occurred from the basis of rejuvenation. In most rejuvenation applications, the goal is to enable the migration of these special cells to the regions in need by activating wound healing mechanisms and initiating the healing process with the effect of growth factors. PRP is counted among these processes.
The application of PRP to the face and neck area helps the skin to have a bright appearance and a healthier appearance as a result of stimulation with its own thrombocytes. Face and neck applications can be done with fine needles or a mesotherapy gun. In addition, PRP can be applied after using a tool called “derma-roller” that opens small and millimetric wells on the skin. This is an effective and comfortable method. In order to obtain an effective result from PRP applications, 4-5 sessions are required at 2-4 weeks. After the sessions are completed, applications can be made in the form of maintenance and less frequently. Since the person’s own blood is applied, this method, which does not have any risk of allergies, results in the stimulation of the tissue, so the efficacy is not limited as in subcutaneous filling materials, but longer. Annual reminders are often preferred. After the procedure, regional redness, bruising, and edema can be observed in the injection areas. These situations are generally not at a level that will affect the patient’s going to work or daily life and spontaneously regress over time.
PRP application cannot be performed in some patients. PRP cannot be performed in liver patients, cancer patients, during pregnancy and breastfeeding, and during acute infections, if the patient has low platelets detected in the blood count. Since PRP is a medical procedure, it is important to evaluate the patient before the procedure and to perform the procedure after the necessary examinations. PRP tubes are also special tubes and the process is safe only if it is done with the right technique in the right tube. The procedure may fail with injections after blood collection and centrifugation, which are not performed with special tubes and the correct technique, and may even cause the development of infections in the skin.